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Sumac-rose water mouthwash versus benzydamine to prevent radiation-induced oral mucositis in head and neck cancers: a phase II randomized trial.

Ahmad AmeriGhazaleh HeydariradRasoul ChoopaniSanaz PoshtmahiPooya AmeriFereshteh TalebiAnahid Bagheri PourFarzad Taghizadeh-Hesary
Published in: Journal of cancer research and clinical oncology (2023)
The sumac-rose group had a lower OM rate and grade and higher QoL than the benzydamine group. In addition, the experimental group developed high-grade OM and oral pain later during the radiotherapy course. Further studies need to be conducted to assess the role of sumac and rose water in reducing grade 3-4 mucositis in patients who undergo chemoradiation for head and neck cancer.
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