Sumac-rose water mouthwash versus benzydamine to prevent radiation-induced oral mucositis in head and neck cancers: a phase II randomized trial.

Ahmad AmeriGhazaleh HeydariradRasoul ChoopaniSanaz PoshtmahiPooya AmeriFereshteh TalebiAnahid Bagheri PourFarzad Taghizadeh-Hesary

Published in: Journal of cancer research and clinical oncology (2023)

The sumac-rose group had a lower OM rate and grade and higher QoL than the benzydamine group. In addition, the experimental group developed high-grade OM and oral pain later during the radiotherapy course. Further studies need to be conducted to assess the role of sumac and rose water in reducing grade 3-4 mucositis in patients who undergo chemoradiation for head and neck cancer.

Keyphrases

radiation induced
phase ii
radiation therapy
high grade
clinical trial
open label
locally advanced
chronic pain
pain management
rectal cancer
neuropathic pain
randomized controlled trial
squamous cell carcinoma
young adults
spinal cord injury
placebo controlled
study protocol
case control