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Real-world effect of a potential drug-drug interaction between topiramate and oral contraceptives on unintended pregnancy outcomes.
Amir Sarayani
Almut Winterstein
Rodrigo Cristofoletti
Valva Vozmediano
Stephan Schmidt
Joshua Brown
Published in:
Contraception (2023)
Our real-world findings confirm clinical pharmacology trials, suggesting that low-dose (≤200 mg/d) topiramate may not influence oral contraceptive effectiveness.
Keyphrases
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pregnancy outcomes
low dose
pregnant women
randomized controlled trial
systematic review
high dose
adverse drug
drug induced
climate change