All-cause and immune checkpoint inhibitor-associated acute kidney injury in immune checkpoint inhibitor users: a meta-analysis of occurrence rate, risk factors and mortality.
Jia-Jin ChenTao-Han LeeGeorge KuoChieh-Li YenCheng-Chia LeeChih-Hsiang ChangKun-Hua TuYung-Chang ChenJi-Tseng FangCheng-Chieh HungChih-Wei YangWen-Chi ChouChing-Chi ChiChin-Ling ChenHuang- Yu YangPublished in: Clinical kidney journal (2023)
Our analysis revealed that approximately 1 in 13 adult ICI recipients may experience all-cause AKI, while 1 in 33 adult ICI recipients may experience ICI-related AKI. Exposure to PPIs and NSAIDs was associated with an increased OR risk for AKI in the current meta-analysis.