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Clinical and molecular parameters associated to pneumonitis development in non-small-cell lung cancer patients receiving chemoimmunotherapy from NADIM trial.

Belén Sierra-RoderoAlberto Cruz-BermúdezErnest NadalYago GaritaonaindíaAmelia InsaJoaquín MosqueraJoaquín Casal-RubioManuel DómineMargarita Majem TarruellaDelvys Rodriguez-AbreuAlex Martinez-MartiJavier De Castro CarpeñoManuel CoboGuillermo López VivancoEdel Del BarcoReyes Bernabé CaroNuria ViñolasIsidoro Barneto ArandaSantiago ViteriBartomeu MassutiRaquel Laza-BriviescaMarta CasarrubiosAránzazu García-GrandeAtocha RomeroFernando FrancoMariano Provencio Pulla
Published in: Journal for immunotherapy of cancer (2022)
Although statistically underpowered, our results shed light on the possible mechanisms behind Pn development, involving innate and adaptative immunity, and open the possibility to predict patients at high risk. If confirmed, this may allow the personalization of both, the surveillance strategy and the therapeutic approaches to manage Pn in patients receiving chemoimmunotherapy.
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