Collagen proportionate area is an independent predictor of long-term outcome in patients with non-alcoholic fatty liver disease.

Elena Buzzetti Andrew Hall Mattias Ekstedt Roberta Manuguerra Marta Guerrero Misas Claudia Covelli Gioacchino Leandro Tu Vinh Luong Stergios Kechagias Emanuel K Manesis Massimo Pinzani Amar P Dhillon Emmanuel A Tsochatzis

Published in: Alimentary pharmacology & therapeutics (2019)

CPA accurately measures fibrosis and is an independent predictor of clinical outcomes in NAFLD; hence it merits further evaluation as a surrogate endpoint in clinical trials.

Keyphrases

clinical trial
liver fibrosis
randomized controlled trial
phase ii
wound healing
tissue engineering
clinical evaluation