Sex differences in nicotine-enhanced Pavlovian conditioned approach in rats.

Sierra J StringfieldAric C MadayagCharlotte A BoettigerDonita L Robinson

Published in: Biology of sex differences (2019)

Drug-naïve females exhibited heightened sign-tracking compared to males, and nicotine enhanced conditioned approach similarly in males and females. Further, non-significant changes to BDNF expression in brain regions highly associated with PCA indicate that BDNF is unlikely to drive nicotine-enhanced conditioned behavior.

Keyphrases

smoking cessation
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stress induced
white matter
resting state
emergency department
multiple sclerosis
functional connectivity
binding protein
brain injury
blood brain barrier
cerebral ischemia