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Rising cases of drug-induced pulmonary fibrosis: Analysis of the Food and Drug Administration Adverse Event Reporting System (FAERS) database, 2000-2022.

Kenneth L McCallKelsey R HennigZachary T AbeDanielle N DattlerKaryssa L HurdSophie L PortnoyZoey J Zagoria
Published in: Pharmacoepidemiology and drug safety (2024)
A 23-year analysis of the FAERS database revealed exponentially increasing adverse event reports of PF. Significant annual increases in reporting of PF suspected with DMARDs and antineoplastic agents were identified. Our study highlights important trends, which should be used to guide PF research related to drugs of potential importance.
Keyphrases
  • adverse drug
  • drug induced
  • liver injury
  • drug administration
  • pulmonary fibrosis
  • electronic health record
  • emergency department
  • human health
  • rheumatoid arthritis
  • rheumatoid arthritis patients
  • climate change