Knockout of ISCA1 causes early embryonic death in rats.

Xinlan YangDan LuXu ZhangWei ChenShan GaoWei DongYuanwu MaLianfeng Zhang

Published in: Animal models and experimental medicine (2019)

Deletion of ISCA1 induced early death in rats. ISCA1 affected the expression of key proteins in the mitochondrial respiratory chain complex, suggesting that ISCA1 has an important influence on the respiratory complex and energy metabolism.

Keyphrases

poor prognosis
oxidative stress
high glucose
diabetic rats
respiratory tract
long non coding rna