SEPP1 polymorphisms modulate serum glucose and lipid response to Brazil nut supplementation.

Janaina Lombello Santos DonadioMarcelo M RogeroElvira M Guerra-ShinoharaCharles DesmarchelierPatrick BorelSilvia M F Cozzolino

Published in: European journal of nutrition (2017)

Supplementation with one Brazil nut a day for 8 weeks reduced total cholesterol and glucose levels. Furthermore, our results suggest that rs3877899 might be associated with glucose concentrations and rs7579 with cholesterol concentrations. Therefore, the effect of genetic variations should be considered in future nutritional interventions evaluating the response to Brazil nut supplementation.

Keyphrases

blood glucose
low density lipoprotein
physical activity
genome wide
metabolic syndrome
dna methylation
copy number
adipose tissue
fatty acid
gestational age
weight loss