Upregulation of the adipokine genes ADIPOR1 and SPP1 is related to poor survival outcomes in colorectal cancer.

Eun Kyung ChoeJin W YiYoung J ChaiKyu J Park

Published in: Journal of surgical oncology (2018)

Upregulation of ADIPOR1 and SPP1, among the adipokine gene family, in cancer tissue is associated with poor survival in CRC, suggesting a potential mechanism linking obesity and CRC. ADIPOR1 and SPP1 expression could become useful prognostic indicators after further validation.

Keyphrases

poor prognosis
cell proliferation
long non coding rna
metabolic syndrome
papillary thyroid
insulin resistance
type diabetes
signaling pathway
weight loss
genome wide
weight gain
squamous cell
gene expression
body mass index
physical activity
human health
genome wide analysis