Effectiveness of a Messenger RNA Vaccine Booster Dose Against Coronavirus Disease 2019 Among US Healthcare Personnel, October 2021-July 2022.
Ian D PlumbNicholas M MohrMelissa HagenRyan WiegandGhinwa K DumyatiKarisa K HarlandAnusha KrishnadasanJade James GistGlen AbediKatherine E Fleming-DutraNora CheaJane LeeDevra BarterMonica BrackneyScott K FridkinLucy E WilsonSara A LovettValerie OcampoErin C PhippsTiffanie M MarcusHoward A SmithlinePeter C HouLilly C LeeGregory J MoranElizabeth KrebsMark T SteeleStephen C LimWalter A SchradingBrian ChinnockDavid G BeiserBrett FaineJohn P HaranUtsav NandiAnne K ChipmanFrank LoVecchioDavid A TalanTamara PilishviliPublished in: Open forum infectious diseases (2023)
A booster dose conferred substantial protection against COVID-19 among healthcare personnel. However, VE was lower during Omicron predominance, and waning effectiveness was observed 4 months after booster dose receipt during this period. Our findings support recommendations to stay up to date on recommended doses of COVID-19 vaccines for all those eligible.