The differential effects of norepinephrine and dopamine on cerebrospinal fluid pressure and spinal cord perfusion pressure after acute human spinal cord injury.
F AltafD E GriesdaleL BelangerL RitchieJ MarkezTamir AilonM C BoydS PaquetteC G FisherJ StreetM F DvorakB K KwonPublished in: Spinal cord (2016)
Norepinephrine was able to maintain MAP with a lower ITP and a correspondingly higher SCPP as compared with dopamine in this study. These results suggest that norepinephrine may be preferable to dopamine if vasopressor support is required post SCI to maintain elevated MAPs in accordance with published guidelines.