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Hydrodehalogenation of Haloarenes by a Sodium Hydride-Iodide Composite.

Derek Yiren OngCiputra TejoKai XuHajime HiraoShunsuke Chiba
Published in: Angewandte Chemie (International ed. in English) (2017)
A simple protocol for hydrodebromination and -deiodination of halo(hetero)arenes was enabled by sodium hydride (NaH) in the presence of lithium iodide (LiI). Mechanistic studies showed that an unusual concerted nucleophilic aromatic substitution operates in the present process.
Keyphrases
  • randomized controlled trial
  • amino acid
  • case control