Hypofractionated stereotactic radiotherapy (HFSRT) versus single fraction stereotactic radiosurgery (SRS) to the resection cavity of brain metastases after surgical resection (SATURNUS): study protocol for a randomized phase III trial.

Maria WaltenbergerDenise BernhardtChristian DiehlJens GemptBernhard MeyerChristoph StraubeBenedikt WiestlerJan J WilkensClaus ZimmerStephanie E Combs

Published in: BMC cancer (2023)

The study was retrospectively registered with ClinicalTrials.gov, number NCT05160818, on December 16, 2021. The trial registry record is available on https://clinicaltrials.gov/study/NCT05160818 . The presented protocol refers to version V1.3 from March 21, 2021.

Keyphrases

phase iii
brain metastases
clinical trial
small cell lung cancer
phase ii
radiation therapy
study protocol
randomized controlled trial
squamous cell carcinoma
rectal cancer