Ovarian expression of follicle stimulating hormone and activin receptors genes in a prenatally-androgenized rat model of polycystic ovary syndrome in adulthood.

Mahsa NoroozzadehMarziyeh Salehi JahromiHanieh GholamiMina AmiriFahimeh Ramezani Tehrani

Published in: Molecular biology reports (2022)

Reduced expression of the FSHR and actR genes in ovarian GCs may be one of the mechanisms mediating PCOS-related disorders, especially abnormal ovarian folliculogenesis and ovulation dysfunction, following exposure to androgens during fetal life.

Keyphrases

polycystic ovary syndrome
insulin resistance
poor prognosis
genome wide
binding protein
depressive symptoms
genome wide identification
oxidative stress
bioinformatics analysis
adipose tissue
type diabetes
metabolic syndrome
gene expression
long non coding rna
skeletal muscle
genome wide analysis