A phase III study of transdermal granisetron versus oral ondansetron for women with gynecologic cancers receiving pelvic chemoradiation.
Shannon D ArmbrusterBryan M FellmanAnuja JhingranPatricia J EifelAnn H KloppRobert L ColemanLois Michelle RamondettaMichael FrumovitzPublished in: Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer (2020)
Transdermal granisetron was 82% more like to control CINV than oral ondansetron in the late phase of cycle 1 and performed similarly to oral ondansetron in all other cycles. Transdermal granisetron should be considered an option as prophylactic antiemetic therapy for gynecologic cancer survivors undergoing chemoradiation.