Login / Signup

Brønsted Acid Mediated Cascade Reaction To Access 3-(2-Bromoethyl)benzofurans.

Stefania PorcuStefania DemuroAlberto LuridianaAndrea CoccoAngelo FrongiaDavid J AitkenFlorence Charnay-PougetRegis GuillotGiorgia SaraisFrancesco Secci
Published in: Organic letters (2018)
A unified protocol for the construction of 3-(2-bromoethyl)benzofurans and 2-(benzofuran-3-yl)ethylamines from bis[(trimethylsilyl)oxy]cyclobutene has been developed. This mild and facile strategy was applied for the synthesis of a series of 5-HT serotonin receptor agonists, underlining its potential for the syntheses of bioactive compounds and natural products.
Keyphrases
  • randomized controlled trial
  • ionic liquid
  • quantum dots
  • reduced graphene oxide
  • highly efficient
  • metal organic framework
  • visible light
  • gold nanoparticles