Altered expression of vesicular trafficking machinery in prostate cancer affects lysosomal dynamics and provides insight into the underlying biology and disease progression.
Bukuru D NturubikaCarlos M GuardiaDavid C GershlickJessica M LoganCarmela MartiniJessica K HeatlieJoanna LazniewskaCourtney MooreGiang T LamKa L LiBen S-Y UngRobert D BrooksShane M HickeyAndrew G BertPhilip A GregoryLisa M ButlerJohn J O'LearyDouglas A BrooksIan R D JohnsonPublished in: British journal of cancer (2024)
These findings provide novel insights into the altered regulation and functional impact of lysosomal vesicular trafficking in prostate cancer pathogenesis.