Connectivity Correlates of Anxiety Symptoms in Drug-Naive Parkinson's Disease Patients.
Rosa De MiccoSara SatolliMattia SicilianoFederica Di NardoGiuseppina CaiazzoAntonio RussoAlfonso GiordanoFabrizio EspositoGioacchino TedeschiAlessandro TessitorePublished in: Movement disorders : official journal of the Movement Disorder Society (2020)
Our findings demonstrated that an abnormal intrinsic connectivity within and between the most reported large-scale networks may represent a potential neural correlate of anxiety symptoms in drug-naive PD patients even in the absence of clinically relevant cognitive impairment. We hypothesize that these specific cognitive and limbic network architecture changes may represent a potential biomarker of treatment response in clinical trials. © 2020 International Parkinson and Movement Disorder Society.
Keyphrases
- end stage renal disease
- clinical trial
- chronic kidney disease
- ejection fraction
- newly diagnosed
- cognitive impairment
- peritoneal dialysis
- sleep quality
- hiv infected
- randomized controlled trial
- emergency department
- functional connectivity
- white matter
- resting state
- physical activity
- depressive symptoms
- adverse drug
- electronic health record