Predicting Symptom Onset in Sporadic Alzheimer Disease With Amyloid PET.
Suzanne E SchindlerYan LiVirginia D BucklesBrian A GordonTammie L S BenzingerGuoqiao WangDean CobleWilliam E KlunkAnne M FaganDavid M HoltzmanRandell J BatemanJohn C MorrisChengjie XiongPublished in: Neurology (2021)
The age at symptom onset in sporadic AD is strongly correlated with the age at which an individual reaches a tipping point in amyloid accumulation.