Effect of Colchicine on Myocardial Injury in Acute Myocardial Infarction.
Nathan MewtonFrançois RoubilleDidier BressonCyril PrieurClaire BouletiThomas BochatonFabrice IvanesOlivier DubreuilLoïc BiereAhmad HayekFrancois DerimayMariama AkodadBenjamin AlosLamis HaiderNaoual El JonhyRachel DawCharles De BourguignonCarole DhelensGérard FinetEric Bonnefoy-CudrazGabriel BidauxFlorent BoutitieDelphine Maucort-BoulchPierre CroisilleGilles RioufolFabrice PrunierDenis AngoulvantPublished in: Circulation (2021)
In this randomized, placebo-controlled trial, oral administration of high-dose colchicine at the time of reperfusion and for 5 days did not reduce IS assessed by cardiac magnetic resonance imaging. Registration: URL: https://www.clinicaltrials.gov; Unique identifier: NCT03156816.
Keyphrases
- acute myocardial infarction
- double blind
- high dose
- magnetic resonance imaging
- left ventricular
- placebo controlled
- percutaneous coronary intervention
- clinical trial
- low dose
- stem cell transplantation
- phase iii
- open label
- phase ii
- computed tomography
- contrast enhanced
- heart failure
- randomized controlled trial
- coronary artery disease
- atrial fibrillation
- acute ischemic stroke
- magnetic resonance
- brain injury