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Prebiotic and Anti-Adipogenic Effects of Radish Green Polysaccharide.

Yu-Ra LeeHye-Bin LeeYoonsook KimKwang-Soon ShinHo-Young Park
Published in: Microorganisms (2023)
Radish ( Raphanus sativus L.) greens are consumed as a source of nutrition, and their polysaccharides such as rhamnogalacturonan-I possess certain beneficial properties. This study investigated the prebiotic effects of a radish green polysaccharide (RGP) on gut health and obesity. The prebiotic activity of RGP was evaluated based on the pH changes and short-chain fatty acids (SCFAs) concentration. The results showed that 0.5% RGP had a higher prebiotic activity score than inulin and increased SCFAs production in all five prebiotic strains. Moreover, RGP inhibited fat accumulation in 3T3-L1 adipocytes, indicating its potential to reduce obesity. Overall, these findings suggested that the polysaccharide of radish greens has prebiotic effects and may serve as a beneficial prebiotic for gut health and obesity.
Keyphrases
  • insulin resistance
  • metabolic syndrome
  • weight loss
  • high fat diet induced
  • type diabetes
  • healthcare
  • public health
  • adipose tissue
  • fatty acid
  • weight gain
  • human health
  • single molecule