Effectiveness and safety of obeticholic acid in a Southern European multicentre cohort of patients with primary biliary cholangitis and suboptimal response to ursodeoxycholic acid.

Elena GomezLuisa Garcia BueyEsther MolinaMarta CasadoIsabel CondeMarina BerenguerFrancisco JorqueraMiguel-Angel SimónAntonio OlveiraManuel Hernández-GuerraMonica MesquitaJose PresaPedro Costa-MoreiraGuilherme MacedoJuan I ArenasJose Manuel SousaJavier AmpueroRosa M MorillasArsenio SantosArmando De CarvalhoJavier UrizJose A CarriónMaria Luisa GutiérrezElia Pérez-FernándezConrado M Fernández Rodrígueznull null

Published in: Alimentary pharmacology & therapeutics (2020)

This study supports data from phase III trials with significant improvement of PBC-Globe continuous prognostic marker score among OCA-treated patients with good tolerability.

Keyphrases

phase iii
open label
double blind
clinical trial
placebo controlled
study protocol
phase ii
electronic health record
randomized controlled trial
deep learning
artificial intelligence
ulcerative colitis