Ni-Catalyzed Site-Selective Dicarboxylation of 1,3-Dienes with CO2.
Andreu TortajadaRyo NinokataRúben MartínPublished in: Journal of the American Chemical Society (2018)
A site-selective catalytic incorporation of multiple CO2 molecules into 1,3-dienes en route to adipic acids is described. This protocol is characterized by its mild conditions, excellent chemo- and regioselectivity and ease of execution under CO2 (1 atm), including the use of bulk butadiene and/or isoprene feedstocks.