Cardiac decompression and right ventricular function improvement after bar removal in patients with pectus excavatum.
Ignacio M RaggioLuzía ToselliMaxroxia ValleDaniela SanjurjoJuan Maria FarinaGastón A Rodriguez-GranilloGaston Bellia-MunzonMarcelo Martínez-FerroPublished in: The international journal of cardiovascular imaging (2024)
Pectus excavatum, the most frequent malformation of the chest wall, has been related to cardiac compression and exercise intolerance. Cardiac outcomes after minimally invasive repair of pectus excavatum with retrosternal implants, particularly after removal (> 2 years postoperative) are generally unknown. We evaluated stress echocardiography outcomes before repair and after bar removal. This study comprised a retrospective cohort of patients with diagnosis of isolated pectus excavatum who underwent stress echocardiography before minimally invasive repair with retrosternal implants, and after bar removal. The diastolic function was evaluated by means of the trans tricuspid flow and tissue doppler imaging. The compression of the atrioventricular groove was assessed using the trans tricuspid gradient and the tricuspid area. We included 43 patients, with a mean age of 15.7 ± 4.0 years (91% male). After bar removal, 83% of patients referred improvement of exercise capacity. Furthermore, we found a significant improvement in right ventricular filling patterns, including a better E/A ratio profile during exercise (p = 0.001), lower filling pressures both at rest (p < 0.0001) and during exercise (p = 0.031), and lower rates of resting paradoxical septal motion [70% vs. 20%, p = 0.0007]. The trans tricuspid mean gradient during exercise was significantly lower after bar removal (p < 0.0001). In this study involving patients with minimally invasive repair of pectus excavatum, we demonstrated a beneficial impact of such intervention after bar removal, with significant improvements related to the right ventricular function, as well as signs of relief of cardiac compression.
Keyphrases
- minimally invasive
- left ventricular
- high intensity
- mitral valve
- aortic stenosis
- aortic valve
- physical activity
- resistance training
- ejection fraction
- transcatheter aortic valve replacement
- randomized controlled trial
- end stage renal disease
- chronic kidney disease
- heart failure
- hypertrophic cardiomyopathy
- pulmonary hypertension
- newly diagnosed
- robot assisted
- metabolic syndrome
- body composition
- type diabetes
- blood flow
- coronary artery disease
- glycemic control