JAK2 as a surface marker for enrichment of human pluripotent stem cells-derived ventricular cardiomyocytes.

Lee Chuen LiewBoon Min PohOmer AnBeatrice Xuan HoChristina Ying Yan LimJeremy Kah Sheng PangLeslie Y BehHenry He YangBoon-Seng Soh

Published in: Stem cell research & therapy (2023)

Our study lays the groundwork for the identification of cardiac subtype surface markers that allow purification of cardiomyocyte sub-populations. Our findings suggest that JAK2 can be employed as a cell surface marker for enrichment of hPSC-derived ventricular-like CMs.

Keyphrases

pluripotent stem cells
cell surface
left ventricular
heart failure
endothelial cells
catheter ablation
high glucose
angiotensin ii
induced pluripotent stem cells
atrial fibrillation