A pilot study on comparison of subjective titration versus remotely controlled mandibular positioning during polysomnography and drug-induced sleep endoscopy, to determine the effective protrusive position for mandibular advancement device therapy.

Elahe KazemeiniSara Op de BeeckAnneclaire VroegopDorine Van LooMarc WillemenJohan VerbraeckenMarc J BraemOlivier M VandervekenMarijke Dieltjens

Published in: Sleep & breathing = Schlaf & Atmung (2022)

This pilot randomized cross-over trial showed no differences in optimal mandibular positioning and corresponding efficacy of MAD between subjective titration, DISE titration or PSG titration.

Keyphrases

drug induced
liver injury
phase iii
sleep quality
study protocol
phase ii
cone beam computed tomography
open label
clinical trial
obstructive sleep apnea
double blind
physical activity
randomized controlled trial
stem cells
adverse drug
bone marrow
electronic health record
clinical evaluation