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The effects of G protein-coupled receptor 30 (GPR30) on cardiac glucose metabolism in diabetic ovariectomized female rats.

Mohammad ShahbazianFaezeh JafarynezhadMaryam YadeghariZeinab FarhadiSanaz Lotfi SamaniMansour EsmailidehajFatemeh SafariHossein Azizian
Published in: Journal of basic and clinical physiology and pharmacology (2022)
In conclusion, our work demonstrates that G-1 as a selective GPR30 agonist is a viable therapeutic approach against T2D and cardiometabolic diseases in multiple preclinical female models.
Keyphrases
  • fatty acid
  • type diabetes
  • left ventricular
  • wound healing
  • cell therapy
  • bone loss
  • heart failure
  • mesenchymal stem cells
  • bone marrow
  • atrial fibrillation