Interventions to improve the appropriate use of polypharmacy in older people: a Cochrane systematic review.
Janine A CooperCathal A CadoganSusan M PattersonNgaire M KerseMarie C BradleyCristín RyanCarmel M HughesPublished in: BMJ open (2015)
The included interventions demonstrated improvements in appropriate polypharmacy based on reductions in inappropriate prescribing. However, it remains unclear if interventions resulted in clinically significant improvements (eg, in terms of hospital admissions). Future intervention studies would benefit from available guidance on intervention development, evaluation and reporting to facilitate replication in clinical practice.