The Impact of Systemic Oncological Treatments on the Fertility of Adolescents and Young Adults-A Systematic Review.

Justine HimpeSander LammerantLore Van den BerghLore D F Lapeire Chloë De Roo

Published in: Life (Basel, Switzerland) (2023)

The effects of chemotherapy on fertility are well investigated, but even in this category, results can be conflicting. Insufficient data are available on the fertility effects of targeted therapy and immunotherapy to draw definitive conclusions. More research is needed for these therapies and their evolving role in treating cancers in AYAs. It would be useful to include fertility endpoints in clinical trials that evaluate new and existing oncological treatments.

Keyphrases

childhood cancer
clinical trial
rectal cancer
locally advanced
radical prostatectomy
randomized controlled trial
robot assisted
prostate cancer
machine learning
electronic health record
big data
atomic force microscopy
high resolution
open label
study protocol
mass spectrometry
high speed
minimally invasive