Recruitment of the m 6 A/m6Am demethylase FTO to target RNAs by the telomeric zinc finger protein ZBTB48.
Syed Nabeel-ShahShuye PuGiovanni L BurkeNujhat AhmedUlrich BraunschweigShaghayegh FarhangmehrHyunmin LeeMingkun WuZuyao NiHua TangGuoqing ZhongEdyta MarconZhaolei ZhangBenjamin J BlencoweJack F GreenblattPublished in: Genome biology (2024)
Our findings thus uncover a previously unknown mechanism of posttranscriptional regulation in which ZBTB48 co-ordinates RNA-binding of the m6A/m6Am demethylase FTO to control expression of its target RNAs.