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Tumor microenvironment-mediated immune profiles and efficacy of anti-PD-L1 antibody plus chemotherapy stratified by DLL3 expression in small-cell lung cancer.

Masayuki ShirasawaTatsuya YoshidaKouya ShiraishiNaoko GotoShigehiro YagishitaTatsuya ImabayashiYuji MatsumotoKen MasudaYuki ShinnoYusuke OkumaYasushi GotoHidehito HorinouchiMasaya YotsukuraYukihiro YoshidaKazuo NakagawaKatsuhiko NaokiTakaaki TsuchidaRyuji HamamotoNoboru YamamotoNoriko MotoiTakashi KohnoShun-Ichi WatanabeYuichiro Ohe
Published in: British journal of cancer (2023)
had a higher neoantigen load, these tumors were resistant to immunochemotherapy due to suppressed tumor immunity by inhibiting antigen-presenting functions.
Keyphrases
  • small cell lung cancer
  • poor prognosis
  • diffuse large b cell lymphoma
  • signaling pathway
  • locally advanced
  • brain metastases
  • case report
  • binding protein
  • long non coding rna
  • squamous cell carcinoma