Assessment of weighted topological overlap (wTO) to improve fidelity of gene co-expression networks.
André VoigtEivind AlmaasPublished in: BMC bioinformatics (2019)
Our analysis demonstrates that, in agreement with previous assumptions, the wTO approach is capable of significantly improving the fidelity of co-expression networks, and that this effect is especially evident for cases of low-sample number gene-expression data sets.