Target-Controlled Continuous Infusion for Antibiotic Dosing: Proof-of-Principle in an In-silico Vancomycin Trial in Intensive Care Unit Patients.

Pieter J ColinStijn JonckheereMichel M R F Struys

Published in: Clinical pharmacokinetics (2019)

Our study shows that adaptive target-controlled infusion has the potential to become a practical tool for patient-tailored antibiotic dosing in the intensive care unit.

Keyphrases

intensive care unit
end stage renal disease
low dose
newly diagnosed
ejection fraction
chronic kidney disease
clinical trial
study protocol
case report
randomized controlled trial
phase iii
mechanical ventilation
risk assessment
climate change
open label
extracorporeal membrane oxygenation