Anti-thrombogenic coatings for devices in neurointerventional surgery: Case report and review of the literature.

Hans HenkesPervinder BhogalMarta Aguilar PérezTim Lenz-HabijanCatrin BannewitzMarcus PetersChristina SengstockOliver GanslandtPedro LylykHermann Monstadt

Published in: Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences (2019)

A variety of ways to reduce the thrombogenicity of neurovascular stents is discussed. Hydrophilic surface coatings are a valid concept to improve the haemocompatibility of neurovascular implants while avoiding the use of dual anti-platelet therapy. Phosphorylcholine and phenox hydrophilic polymer coating are currently the most promising candidates. This concept is supported by anecdotal experience. However, formalised registries and randomised trials are currently being established.

Keyphrases

liquid chromatography
minimally invasive
clinical trial
open label
coronary artery bypass
study protocol
mass spectrometry
solid phase extraction
randomized controlled trial
surgical site infection
high resolution
acute coronary syndrome
percutaneous coronary intervention