Causal pathways to health-related quality of life in children with juvenile idiopathic arthritis: results from the ReACCh-Out cohort.

Kiem OenJiahao TianThomas M LoughinNatalie J ShiffLori B TuckerAdam M HuberRoberta A BerardDeborah M LevyDax G RumseyShirley M TseMercedes ChanBrian M FeldmanCiaran M DuffyJaime Guzmannull null

Published in: Rheumatology (Oxford, England) (2021)

Our findings support disease activity and treatment intensity as being root causes of decreased HRQoL in children with JIA, with pain, functional impairments, and participation restrictions being mediators for disease activity; they support psychosocial effects and side effects as being mediators for treatment intensity.

Keyphrases

disease activity
juvenile idiopathic arthritis
systemic lupus erythematosus
rheumatoid arthritis
rheumatoid arthritis patients
ankylosing spondylitis
chronic pain
physical activity
mental health
pain management
spinal cord injury