LncRNA-WAKMAR2 regulates expression of CLDN1 to affect skin barrier through recruiting c-Fos.
Yunhua TuLi WangXiaoli WangWenjuan WuYing TuDandan ZouYuanyuan DengJue QiCan CaoDan XuYanjie ChaiYun ZhuJuan ZhangJun SunFan LaiLi He
Published in: Contact dermatitis (2022)
We identified a crucial LncRNA (WAKMAR2) for the protection of the skin barrier in vitro and in vivo. Mechanically, it can specifically interact with c-Fos protein for the regulation of CLDN1, a finding which could be applied for CAD treatment.