PD-L1, B7-H3 and VISTA are highly expressed in gestational trophoblastic neoplasia.

Liju ZongMing ZhangWenze WangXirun WanJunjun YangYang Xiang

Published in: Histopathology (2019)

The GTN trophoblast cells show high expression of PD-L1, B7-H3 and VISTA in a manner that is independent of clinical outcomes. These proteins may be potential immunotherapeutic targets when treating GTN.

Keyphrases

induced apoptosis
poor prognosis
weight gain
cell cycle arrest
pregnant women
high grade
binding protein
oxidative stress
signaling pathway
birth weight
physical activity
long non coding rna
cell proliferation
pi k akt