Prognostic Utility of CD47 in Cancer of the Uterine Cervix and the Sensitivity of Immunohistochemical Scores.
Angel YordanovVelizar ShivarovStoyan KostovYonka IvanovaPolina DimitrovaSavelina PopovskaEva TsonevaMariela Vasileva-SlavevaPublished in: Diagnostics (Basel, Switzerland) (2022)
The expression of CD47 in the cancer cells is prognostic for tumor invasion in the surrounding structures, independent of lymph node engagement. The H-score is the most sensitive immunohistochemical score to describe tumor stage. To the best of our knowledge, this is the first study evaluating the significance of CD47 expression in CUC.