Tranexamic acid inhibits melanogenesis partially via stimulation of TGF-β1 expression in human epidermal keratinocytes.
Xiaoxue XingZhongyi XuLi ChenShanglin JinChengfeng ZhangLeihong Flora XiangPublished in: Experimental dermatology (2021)
TA could stimulate TGF-β1 expression in keratinocytes, which further inhibits melanogenesis through the paracrine signaling.