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Endovascular Thrombectomy for Large Ischemic Strokes with ASPECTS 0-2: a Meta-analysis of Randomized Controlled Trials.

Laurens WinkelmeierMáté MarosFabian FlottmannChristian HeitkampGerhard SchönGötz ThomallaJens FiehlerUta Hanning
Published in: Clinical neuroradiology (2024)
This meta-analysis suggests a treatment effect of endovascular thrombectomy in specific patients with very low ASPECTS of 0-2, challenging the use of ASPECTS for treatment selection in acute ischemic stroke due to large vessel occlusion. An individual patient meta-analysis of RCTs would strengthen evidence in the treatment of patients with ASPECTS of 0-2.
Keyphrases
  • systematic review
  • randomized controlled trial
  • acute ischemic stroke
  • oxidative stress