Long non-coding RNA TPT1-AS1 inhibits ferroptosis in ovarian cancer by regulating GPX4 via CREB1 regulation.

Lei CaoYan WangJuanni LiuXiaoying BaiXiaohong Chi

Published in: American journal of reproductive immunology (New York, N.Y. : 1989) (2024)

TPT1-AS1 promotes OC progression by inhibiting ferroptosis and upregulating CREB1, forming a regulatory axis with KHDRBS3. These findings highlight the regulatory network involving lncRNAs, RBPs, and transcription factors in cancer progression.

Keyphrases

long non coding rna
transcription factor
poor prognosis
cell death
papillary thyroid
genome wide identification
signaling pathway
dna binding
network analysis
childhood cancer
young adults