Automated T2 relaxometry of the hippocampus for temporal lobe epilepsy.
Gavin P WinstonSjoerd B VosJane L BurdettM Jorge CardosoSebastien OurselinJohn S DuncanPublished in: Epilepsia (2017)
Automated hippocampal segmentation can be reliably extended to the determination of hippocampal T2 values, and a combination of hippocampal volumes and T2 values can separate subjects with HS from healthy controls. There is good agreement with manual measurements, and the technique is more reproducible on repeat scans than manual measurement. This protocol can be readily introduced into a clinical workflow for the assessment of patients with focal epilepsy.
Keyphrases
- temporal lobe epilepsy
- deep learning
- machine learning
- high throughput
- cerebral ischemia
- randomized controlled trial
- computed tomography
- convolutional neural network
- magnetic resonance imaging
- cognitive impairment
- solid phase extraction
- mass spectrometry
- molecularly imprinted
- high resolution
- tandem mass spectrometry
- prefrontal cortex
- liquid chromatography