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KCNA1 promotes the growth and invasion of glioblastoma cells through ferroptosis inhibition via upregulating SLC7A11.
Weichao Wang
Yang Zhang
Xuetao Li
Qinzi E
Zuoyu Jiang
Qikun Shi
Yu Huang
Jian Wang
Yulun Huang
Published in:
Cancer cell international (2024)
Therefore, our research suggests that KCNA1 may promote tumor growth and invasion by upregulating the expression of SLC7A11 and inhibiting ferroptosis, making it a promising therapeutic target for GBM.
Keyphrases
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cell death
cell cycle arrest
cell migration
induced apoptosis
poor prognosis
signaling pathway
endoplasmic reticulum stress
oxidative stress
binding protein
cell proliferation
long non coding rna
pi k akt