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KCNA1 promotes the growth and invasion of glioblastoma cells through ferroptosis inhibition via upregulating SLC7A11.

Weichao WangYang ZhangXuetao LiQinzi EZuoyu JiangQikun ShiYu HuangJian WangYulun Huang
Published in: Cancer cell international (2024)
Therefore, our research suggests that KCNA1 may promote tumor growth and invasion by upregulating the expression of SLC7A11 and inhibiting ferroptosis, making it a promising therapeutic target for GBM.
Keyphrases
  • cell death
  • cell cycle arrest
  • cell migration
  • induced apoptosis
  • poor prognosis
  • signaling pathway
  • endoplasmic reticulum stress
  • oxidative stress
  • binding protein
  • cell proliferation
  • long non coding rna
  • pi k akt