Upregulation of MicroRNA-34a Sensitizes Ovarian Cancer Cells to Resveratrol by Targeting Bcl-2.

Shangli Yao Ming Gao Zujun Wang Wenyan Wang Lei Zhan Bing Wei

Published in: Yonsei medical journal (2021)

Overall, these results demonstrated that REV exerts anti-cancer effects on OC cells through an miR-34a/Bcl-2 axis, highlighting the therapeutic potential of REV for treatment of OC.

Keyphrases

induced apoptosis
cell proliferation
signaling pathway
long non coding rna
endoplasmic reticulum stress
cell cycle arrest
poor prognosis
long noncoding rna
cell death
combination therapy