Leptomeningeal metastasis of breast cancer during neo-adjuvant chemotherapy in a 38-year-old woman: a case report.
Yao JinJinglu LuTing ZhangShenqiang YanHuihui ChenKun ZhangYi-Ding ChenJiao-Jiao ZhouPublished in: AME case reports (2024)
Breast cancer metastasis to the brain, especially LM, should be given sufficient vigilance and attention at the beginning of the diagnosis and treatment, particularly in triple-negative breast cancer patients who are at high risk. Symptoms of LM may be masked by the chemotherapy adverse effects. The results of MRI and CT may show negative results, thus lumbar puncture with CSF should be done promptly if LM is highly suspected in clinical practice. Early prevention, early detection and timely treatment are crucial according to the poor prognosis.
Keyphrases
- poor prognosis
- long non coding rna
- contrast enhanced
- clinical practice
- magnetic resonance imaging
- computed tomography
- minimally invasive
- image quality
- resting state
- white matter
- magnetic resonance
- diffusion weighted imaging
- dual energy
- locally advanced
- ultrasound guided
- small cell lung cancer
- brain injury
- functional connectivity
- positron emission tomography
- depressive symptoms
- radiation therapy
- multiple sclerosis
- blood brain barrier
- cerebral ischemia
- subarachnoid hemorrhage
- pet ct
- smoking cessation
- chemotherapy induced