Clinically uninvolved but not healthy-The skin of patients with atopic dermatitis is primed for itch and inflammation.
S MoonO Stasikowska-KanickaMalgorzata Wagrowska-DanilewiczMarlena HawroMartin MetzMarcus MaurerTomasz HawroPublished in: Journal of the European Academy of Dermatology and Venereology : JEADV (2023)
The non-lesional skin of AD patients markedly differs from healthy skin in cowhage-induced itch responses and the expression of receptors for proteases and histamine. Proactive therapeutic interventions that downregulate these receptors may prevent episodic exacerbation in AD.