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Response-shift effects in neuromyelitis optica spectrum disorder: estimating response-shift-adjusted scores using equating.

Carolyn Emily SchwartzRoland B StarkBrian D StuckyYuelin LiBruce D Rapkin
Published in: Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation (2021)
Our results reveal notable treatment group differences in MCS but not PCS response shifts, which can explain null results detected in previous work. The method introduced herein provides a way to provide further information about response-shift effects in clinical trial data.
Keyphrases
  • clinical trial
  • spectrum disorder
  • healthcare
  • machine learning
  • genome wide
  • dna methylation
  • study protocol
  • smoking cessation
  • deep learning
  • phase ii
  • double blind
  • combination therapy
  • placebo controlled