Formal (4 + 1)-Addition of Allenoates to o-Quinone Methides.
Katharina ZielkeMario WaserPublished in: Organic letters (2018)
The first (4 + 1)-annulation of o-quinone methides with α-branched allenoates as C1 synthons has been developed. This operationally simple protocol gives access to highly functionalized dihydrobenzofurans in an unprecedented fashion with excellent diastereoselectivities and high yields.