Human amniotic stem cells improve hepatic microvascular dysfunction and portal hypertension in cirrhotic rats.
Giada PietrosiAnabel Fernández-IglesiasMariangela PampaloneMartí Ortega-RiberaJuan J LozanoHéctor García-CalderóLaia Abad-JordàPier G ConaldiOrnella ParoliniGiovanni VizziniAngelo LucaJaime BoschJordi Gracia-SanchoPublished in: Liver international : official journal of the International Association for the Study of the Liver (2020)
This preclinical study shows that infusion of human amniotic stem cells effectively decreases PP by ameliorating liver microcirculation, suggesting that it may represent a new treatment option for advanced cirrhosis with portal hypertension.